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After his painter wife (Catherine Keener) leaves him and takes their daughter to Berlin, theater director Caden Cotard (Philip Seymour Hoffman) stages a new autobiographical play in a massive warehouse amid a life-size replica of Manhattan. Meanwhile, Caden must contend with the many women in his life — including a box-office worker, an actress and a shrink — in this beguiling directorial debut (nominated for three Independent Spirit Awards) by ace screenwriter Charlie Kaufman.
